Abstract

Fluidic engineering challenges in the development of an electronic based DNA identification system

Integrated Nano-technologies has spent the last three and a half years developing a novel electronic based DNA identification system. In addition to combining DNA with microelectronics to form sensors that respond to, and identify DNA sequences in target organisms; this system relies heavily on the manipulation and delivery of small volumes of fluids. These fluids facilitate both the biological and chemical reactions required by the device's processes. The company has encountered fluidic engineering challenges throughout the development of the system including:

- pump accuracy
- material incompatibilities
- adhesive intrusion
- reaction waste collection
- micro mixing/channel design

The presentation will discuss these challenges and the approaches taken to overcome them. He will also give an overview of the device that takes advantage of these innovations.

Brief Bio

Michael Connolly, PhD is the founder, President and CEO of Integrated Nano-Technolgies, a nano-scale research and development company. He has a PhD in molecular biology from Northwestern University and completed a post-doctoral fellowship in the Department of Microbiology at the University of Illinois Medical Center in Chicago. After completing his JD at Cornell University, he practiced patent law at Nixon Peabody, LLP. As an attorney, he played a significant role in developing the licensing strategy for a major genomics company, as well as patenting, protecting and licensing technologies for several other companies and universities.